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KMID : 0948320070070020069
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Konyang Medical Journal
2007 Volume.7 No. 2 p.69 ~ p.73
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CT Fluoroscopy-guided Automatic Needle Biopsy for Pulmonary Nodules Smaller than 15 mm : Analysis of Successful Biopsy Rate and Frquency of Complication
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Cho Young-Jun
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Abstract
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Purpose: To evaluate the usefulness of CT fluoroscopic guided percutaneous needle biopsy for pulmonary nodules smaller than 15 mm in diameter.
Materials and Methods : Forty-three patients with pulmonary nodules smaller than 15 mm underwent CT fluoroscopic guided percutaneous biopsy. We evaluated the accuracy, sensitivity, specificity, positive and negative predictive value for the definitive diagnosis of benignity or malignancy and complications of biopsy. We analyzed the
relationship between diagnostic accuracy and the size of the nodule, distance from the pleural surface, location of the
nodule, and number of biopsy.
Results: In 42 of 43 nodules, definitive diagnoses of benignity or malignancy could be established. Among them, 14 were malignant and 28 were benign. The overall diagnostic accuracy was 95.2%. The sensitivity and the specificity
were 85.7% and 100%, respectively. The positive and negative predictive values were 100% and 93.3%, respectively.
However, there was not a statistical significance between diagnostic accuracy and the size of the nodule, distance
from the pleural surface, location of the nodule, and number of biopsy (p＞0.05). Complication after biopsy were pneumothorax in 8 patients and parenchymal hemorrhage in 21.
Conclusion: CT fluoroscopic guided percutaneous biopsy for pulmonary nodules smaller than 15 mm is useful procedure due to its high diagnostic accuracy and safety.
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KEYWORD
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Lung biopsy, Lung, CT, Fluoroscopy
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